Elim Biopharm

Peptide Synthesis

With overnight peptide synthesis, we can get your data moving fast! Our highly customizable peptides fit each customer’s need, no matter how big, small, or complex.

Elim’s Unprecedented Combination of

Quality, Speed and Cost Advantage

Elim Bio revolutionized the field of peptide synthesis by being the first company to offer overnight peptide synthesis. We can meet and exceed all of your peptide needs by synthesizing high quality peptides from the best starting materials. We also provide FREE delivery for our local customers and guarantee you will be satisfied with our service.    Learn More

Overnight Synthesis of 10mer or Less

Peptide Array, Epitope Mapping

Custom, Modified Peptide Synthesis

Elim Peptide Synthesis

Key Features

Become one of Elim’s thousands of satisfied customers. Once you witness Elim’s outstanding quality and customer service, you will understand why scientists from top research institutes to biotech to pharmaceutical companies are using Elim’s peptide synthesis services.

Fastest turnaround in the industry

  • For peptide length of 10AA or less, an overnight service is available to you. (Crude, unmodified, amorphous products only. One more day will be added to lyophilized products). Order cut-off time is 12 noon Pacific Standard Time.
  • Regular turnaround time is 3-7 days for regular peptides. For special peptides and purification needs, additional time may be necessary.
  • Peptide Arraysas fast as 2-3 day delivery!

Special Pricing

Elim offers competitive pricing for all peptide synthesis products. Please email us at Peptide@ElimBio.com for a specific quote.

High-quality

Elim employs fine-tuned synthesis protocols, stringent QA/QC procedures, and state-of-the-art instrumentations such as an array of high-end mass spectrometers to assure that only high-quality products are synthesized and delivered. Our highly trained technicians, automated systems and state of the art robotics will bring you reliable products consistently.

Convenient Online ordering system.

You may place peptide order online at our web site: www.elimbio2.com. Please log in, click “Custom Peptide Synthesis” and follow the instructions.

Elim Peptide Synthesis

Specifications

Still waiting for your peptides? Frustrated with the quality of your current supplier? Please try Elim’s Peptide Synthesis and give us a chance to impress you. Due to the characteristics of the traditional peptide synthesis chemistry, it usually takes 2-6 weeks for other vendors, and sometimes even longer to deliver a peptide. Through a unique setup, Elim has reduced the turnaround time for peptide synthesis from weeks to days for regular peptides. We are continuously improving our services to better suite your research goals. We look forward to working with you!

To place your Custom Peptide Synthesis order, please click here, or to first receive a quote for your peptide, please click here. You will be directed to a page that will guide you through the ordering process.

  • We only use top quality starting materials and solvents
  • We provide Mass Spec and HPLC analysis for quality assurance
  • Growing customer converts to our company commit to use only our service!
  • PhD experts ready to answer any of your synthesis related questions
  • Overnight peptide synthesis for crude unmodified, amorphous peptides up to 10mer
  • As fast as 3-7 days for regular peptides
    Try and Witness the Difference!
  • Accurately and efficiently synthesize 3-50+ amino acid peptides
  • Provide various levels of purity (Crude, >70%, >80%, >90%, >95%, >98%)
    • Crude (amorphous, or lyophilized)
    • >70%
    • >80%
    • >90%
    • >95%
    • >98%
  • Other special requirements, please inquire.
  • C-terminal: acid (default), amide, biotin, AMC, etc.
  • Internal modifications: biotin, dansyl, phosphorylation, etc.
  • Cyclization (disulfide bond, head-to-tail)
  • Please inquire for other modifications
  • 1-5 mg
  • 5-10 mg
  • 10-20 mg
  • 20-50 mg
  • 50-100 mg
  • Larger than 100 mg scales, please inquire.

Elim Peptide Synthesis

Peptide Arrays

Try our peptide array services and give us a chance to impress you. Avoid the long industry turnaround time for peptide delivery by allowing Elim to be your peptide array provider. Due to the characteristics of the traditional peptide synthesis chemistry, it can take 2-6 weeks or longer for other vendors to deliver a peptide array. Through a unique setup, Elim has reduced the turnaround time for peptide array synthesis from weeks to days for peptide arrays. We are continuously improving our services to better suite your research goals. We look forward to working with you!

Most Versatile Peptide Array

  • Antibody and T-cell epitope mapping and optimization
  • Peptide libraries
  • Protein characterization
  • Drug screening, vaccine target validation

Highest Quality Peptide Arrays

  • We only use top quality starting materials and solvents
  • we provide mass spec and HPLC analysis for quality assurance
  • PhD experts ready to answer any of your synthesis related questions

Most Economic Peptide Array

  • Crude, amorphous, C-terminal amide peptides only
  • 1-5mg synthesis scale
  • Up to 20 amino acids per peptide
  • No minimum number of peptides

Fastest Turn Around Time

  • As fast as 2-day delivery!
  • High quality crude peptides in 96-well plate format

To order peptide arrays, please email us at Peptide@ElimBio.com with either of the following information:

  • Peptide sequences in your peptide arrays
  • Protein sequence, with the length of the peptide, and how many amino acid overlap you desire.If you have any questions or comments please feel free to contact us.

Ordering Elim DNA Services

Peptides & Peptide Arrays

If you already have an online account, Please login to place a DNA sequencing order.

If you do not have an Elim Bio account, please register first to generate an online account. Then, you may immediately login to place a DNA sequencing order. You may use the same account for all Elim services such as DNA sequencing, oligo synthesis, and peptide synthesis.

Quotation for Custom Peptides

To receive a quote before you order, please E-mail us (Peptide@ElimBio.com)with your:

  • Peptide sequence
  • Quantity (mg)
  • Purity (Crude, >70%, >80%, >90%, >95%, >98%)
  • Desired modifications, if any
  • Any other specifications such as: special timeline requirements, shipping requirements, and additional questions.
  • We offer competitive pricing, and will do our best to work with your budget. Feel free to include a competitor’s quote.

Order Custom Peptides

Please login to your existing account to place a Peptide Synthesis order. You may use the same account for all other Elim Services, including DNA sequencing and Oligo synthesis.

If you do not have an Elim Bio account, please register first to generate an online account (real-time). Then, you may immediately login to begin placing a peptide synthesis order.

Place your order under “Order Custom Peptides”, and follow the instructions and include any special instructions in the “Remarks Section” of the order.

Free Local Sample Pickup

For local customers in the San Francisco Bay Area, Elim offers free delivery of your peptide orders. If you are not sure, please call us at (800) 214-7722 or (510) 783-1112 to check whether free delivery is currently available for your institute or business. Free peptide delivery will automatically apply if you already have free DNA sequencing sample pickup or oligo delivery.

If you have any questions or comments please feel free to contact us.

Ordering Peptide Arrays

Please email us at Peptide@ElimBio.com with your sequences for peptide arrays:

  • Peptide sequences in your peptide arrays
  • Protein sequence, with the length of the peptide, and how many amino acid overlap you desire.

Custom Stable Isotope Labeled (SIL) Peptides

for LC-MS Protein Quantification, Quantitative Proteomics, and Other Applications
Stable Isotope labeled (SIL) peptides sometimes are also called heavy isotope peptides. They contain stable isotope labeled amino acids, and share the same physiochemical properties with their non-labeled counterparts. Stable isotopes are non-radioactive chemical isotopes that do not decay spontaneously.

Peptides labeled with heavy stable isotopes have many applications, such as:

Pharmacokinetic studies of biologics (protein drugs, antibodies, etc.). Stable isotope labeled peptides are the ideal internal standards for LC-MS based protein quantification studies. In such experiments, the mass-shifted, stable isotope labeled peptide calibrator is spiked into the sample of interest, and allows quantification from a simple ratio of the labeled peak to the unlabeled. This is also called stable isotope dilution method, and is the basis for all LC-MS selective reaction monitoring (SRM) and multiple reaction monitoring (MRM) methods.

SIL peptides is also an important tool in NMR spectroscopy studies for characterization of protein structures, protein dynamics, protein-protein interactions, and identification of ligand binding sites in drug discovery. Incorporation of stable isotopes that have a non-zero spin such as 2H (spin 1), 13C (spin ½), and 15N (spin ½) into selected positions of a protein or peptide can be very helpful in resolving their NMR structures.

Reference materials for quantitative proteomics. LC-MS based proteomics methods can be multiplexed, so that hundreds to thousands of proteins can be quantified in a single assay.

Absolute quantification of target protein and post-translational modifications in complex protein mixtures.

Other applications include:

  • Metabolite ID studies.
  • Verification of outcomes derived from RNAi experiments.
  • Protein expression tracking.
  • Cell signal profiling and pathway recognition studies.
  • Biomarker discovery studies,
  • and many more.

ElimBio offer customized solution for SIL peptide products, including SIL labeling site designing, peptide products, peptide QC (HPLC purity and MS identification), peptide content for quantitation, and etc. Experienced Ph. D. chemists will help you to design the most efficient SIL peptides for your experiments with the lowest cost.  We can provide custom peptides labeled with stable isotopes including:

2H
(deuterium)

13C

15N & 13C combinations

15N

The table below lists the most common stable isotopically labeled amino acids. Other labeled amino acids are available upon request.

Amino Acid One-Letter Code Isotope Mass Difference
Alanine A U- 13C3, U-15N +4 Da
Arginine R U- 13C6, U-15N4 +10 Da
Leucine L U- 13C6, U-15N +7 Da
Lysine K U- 13C6, U-15N2 +8 Da
Phenylalanine F U- 13C9, U-15N +10 Da
Proline P U- 13C5, U-15N +6 Da
Valine V U- 13C5, U-15N +6 Da

Available Modifications

  • Fluorescence and Dye labeling
  • Fatylation
  • Unsual Amino Acids
  • Phosphorylation
  • Cyclization
  • PEG spacer
  • Click chemistry
  • Stapled peptide
  • BSA or KLH conjugation

For other modifications, please email peptide@elimbio.com.

Custom SIL Designing & Production

For details, please email peptide@elimbio.com:

  • Your peptide sequence, and any desired modifications, such as Carbamidomethylation of Cysteine, or phosphorylation, etc.  SIL can be incorporated in combination with any of our peptide modifications.
  • Your desired peptide quantity
  • Your desired peptide purity

Deliverables

  • Lyophilized isotopically labeled peptide of specified quantity and purity
  • QC reports including: HPLC chromatogram, MS spectra, Certificate of Analysis, vials, 96 well plate, Micronic plate

Peptide Synthesis FAQs

Can I receive a quote for my peptides before I place a peptide order?

Yes. New customers prefer receiving a quote for their peptide before placing their order. Generally, as customers become familiar with our pricing, they tend place their peptide orders without first receiving a quote.

In what format do you deliver your peptides?

We can deliver our peptides in an amorphous form or lyophilize them before shipping them to you. Peptides in the lyophilized state are more stable at normal ambient temperatures.

How fast do you turn around your peptides?

We can turn around peptides as fast as overnight. However, the total time required depends on the specifics of your order including the required modifications, purity as well as the length of your peptides. For peptide lengths of 10 or less, an overnight service is available to you. (Crude, unmodified, amorphous products only. One more day will be added to lyophilized products). Order cut-off time is 10am. Regular turnaround time is 3-7 days for regular peptides. For special peptides and purification needs, additional time will be needed. Also, for peptide arrays, we have the potential for a 2 day turnaround time (Crude, amorphous, 1-5mg scale, <20AA only).

If I want a peptide array, but don’t have 96 peptides, how will I be charged?

Peptide arrays are priced per peptide and not by array. We can synthesize just a few to a full plate of peptides according to your specific peptide array needs.

Can you make modifications on peptides?
Yes. Please go to our “Custom Peptide Synthesis” page to see a list of our modifications. If you require a modification that is not present, please contact us and we will try work to accommodate.
When will my peptide synthesis be started?
We start your peptide synthesis as soon as your order is placed online. If you require any changes to your order, please call (800.214.7722 or 510.783.1112) and email us immediately so that we can make modifications as well.
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